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Circulating Platelet-activating Factor is Primarily Cleared by Transport, not Intravascular Hydrolysis by Lipoprotein-associated Phospholipase A(2) / PAF Acetylhydrolase
RATIONALE: The phospholipid Platelet-activating Factor (PAF) stimulates all cells of the innate immune system, and numerous cardiovascular cells. A single enzyme [plasma PAF acetylhydrolase (PAF-AH) or Lipoprotein-associated Phospholipase A(2) (Lp-PLA(2))] in plasma hydrolyzes PAF, but significant c...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3057131/ https://ncbi.nlm.nih.gov/pubmed/21183738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.228742 |
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