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The role of inhibitory phosphorylation of CDC2 following DNA replication block and radiation-induced damage in human cells.

It has been suggested that the survival response of p53 defective tumor cells to agents that inhibit DNA replication or damage DNA may be largely dependent on cell cycle checkpoints that regulate the onset of mitosis. In human cells, the mitosis-inducing kinase CDC2/cyclin B is inhibited by phosphor...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Principais autores: Blasina, A, Paegle, E S, McGowan, C H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Cell Biology 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305710/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9201712/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.8.6.1013
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