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Hydrophobic Aided Replica Exchange: an Efficient Algorithm for Protein Folding in Explicit Solvent

A hydrophobic aided replica exchange method (HAREM) is introduced to accelerate the simulation of all-atom protein folding in explicit solvent. This method is based on exaggerating the hydrophobic effect of various protein amino acids in water by attenuating the protein-water attractive interactions...

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Hlavní autoři: Liu, Pu, Huang, Xuhui, Zhou, Ruhong, Berne, B. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057047/
https://ncbi.nlm.nih.gov/pubmed/16986898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp060365r
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