Quantification of Oxidative DNA Lesions in Tissues of Long-Evans Cinnamon Rats by Capillary High-performance Liquid Chromatography-Tandem Mass Spectrometry Coupled with Stable Isotope-dilution Method

The purpose of our study was to develop suitable methods to quantify oxidative DNA lesions in the setting of transition metal-related diseases. Transition metal-driven Fenton reactions constitute an important endogenous source of reactive oxygen species (ROS). In genetic diseases with accumulation o...

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Hauptverfasser: Wang, Jin, Yuan, Bifeng, Guerrero, Candace, Bahde, Ralf, Gupta, Sanjeev, Wang, Yinsheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056914/
https://ncbi.nlm.nih.gov/pubmed/21323344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac103099s
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