The Catastrophe-promoting Activity of Ectopic Op18/Stathmin Is Required for Disruption of Mitotic Spindles But Not Interphase Microtubules

Oncoprotein18/stathmin (Op18) is a microtubule (MT) destabilizing protein that is inactivated during mitosis by phosphorylation at four Ser-residues. Op18 has at least two functions; the N-terminal region is required for catastrophe-promotion (i.e., transition from elongation to shortening), while t...

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Detalles Bibliográficos

Publicado en:	Mol Biol Cell
Principais autores:	Holmfeldt, Per, Larsson, Niklas, Segerman, Bo, Howell, Bonnie, Morabito, Justin, Cassimeris, Lynne, Gullberg, Martin
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Cell Biology 2001
Assuntos:	Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30569/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160824/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.1.73
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