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Comparing methods to estimate treatment effects on a continuous outcome in multicentre randomized controlled trials: A simulation study

BACKGROUND: Multicentre randomized controlled trials (RCTs) routinely use randomization and analysis stratified by centre to control for differences between centres and to improve precision. No consensus has been reached on how to best analyze correlated continuous outcomes in such settings. Our obj...

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Detalhes bibliográficos
Main Authors: Chu, Rong, Thabane, Lehana, Ma, Jinhui, Holbrook, Anne, Pullenayegum, Eleanor, Devereaux, Philip James
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056845/
https://ncbi.nlm.nih.gov/pubmed/21338524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2288-11-21
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