Carregant...

Aberrant Anaplastic Lymphoma Kinase Activity Induces a p53 and Rb-Dependent Senescence-Like Arrest in the Absence of Detectable p53 Stabilization

Anaplastic Lymphoma Kinase (ALK) is a receptor tyrosine kinase aberrantly expressed in a variety of tumor types, most notably in Anaplastic Large Cell Lymphoma (ALCL) where a chromosomal translocation generates the oncogenic fusion protein, Nucleophosmin-ALK (NPM-ALK). Whilst much is known regarding...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: McDuff, Fiona Kate Elizabeth, Turner, Suzanne Dawn
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056788/
https://ncbi.nlm.nih.gov/pubmed/21423761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017854
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!