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Insulin-like growth factor-I gene delivery to astrocytes reduces their inflammatory response to lipopolysaccharide
BACKGROUND: Insulin-like growth factor-I (IGF-I) exerts neuroprotective actions in the central nervous system that are mediated at least in part by control of activation of astrocytes. In this study we have assessed the efficacy of exogenous IGF-I and IGF-I gene therapy in reducing the inflammatory...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3056784/ https://ncbi.nlm.nih.gov/pubmed/21371294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-21 |
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