Insulin-like growth factor-I gene delivery to astrocytes reduces their inflammatory response to lipopolysaccharide

BACKGROUND: Insulin-like growth factor-I (IGF-I) exerts neuroprotective actions in the central nervous system that are mediated at least in part by control of activation of astrocytes. In this study we have assessed the efficacy of exogenous IGF-I and IGF-I gene therapy in reducing the inflammatory...

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Detalles Bibliográficos
Main Authors: Bellini, Maria J, Hereñú, Claudia B, Goya, Rodolfo G, Garcia-Segura, Luis M
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056784/
https://ncbi.nlm.nih.gov/pubmed/21371294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-21
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