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Recent evolution of the NF-κB and inflammasome regulating protein POP2 in primates

BACKGROUND: Pyrin-only protein 2 (POP2) is a small human protein comprised solely of a pyrin domain that inhibits NF-κB p65/RelA and blocks the formation of functional IL-1β processing inflammasomes. Pyrin proteins are abundant in mammals and several, like POP2, have been linked to activation or reg...

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Detalhes bibliográficos
Main Authors: Atianand, Maninjay K, Fuchs, Travis, Harton, Jonathan A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056782/
https://ncbi.nlm.nih.gov/pubmed/21362197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-11-56
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