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Exocytotic mechanism studied by truncated and zero layer mutants of the C-terminus of SNAP-25
The highly conserved SNARE proteins, SNAP-25, syntaxin and synaptobrevin, form a tight ternary complex, which is essential for exocytosis. Crystallization of this complex revealed a four-helix bundle with an unusual hydrophilic layer (zero layer) in its center. In order to evaluate the role of this...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305669/ https://ncbi.nlm.nih.gov/pubmed/10716928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.6.1279 |
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