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Exocytotic mechanism studied by truncated and zero layer mutants of the C-terminus of SNAP-25

The highly conserved SNARE proteins, SNAP-25, syntaxin and synaptobrevin, form a tight ternary complex, which is essential for exocytosis. Crystallization of this complex revealed a four-helix bundle with an unusual hydrophilic layer (zero layer) in its center. In order to evaluate the role of this...

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Detaylı Bibliyografya
Asıl Yazarlar: Wei, Shunhui, Xu, Tao, Ashery, Uri, Kollewe, Astrid, Matti, Ulf, Antonin, Wolfram, Rettig, Jens, Neher, Erwin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2000
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC305669/
https://ncbi.nlm.nih.gov/pubmed/10716928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.6.1279
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