WT1 Mutation and 11P15 Loss of Heterozygosity Predict Relapse in Very Low-Risk Wilms Tumors Treated With Surgery Alone: A Children's Oncology Group Study

PURPOSE: Children's Oncology Group defines very low-risk Wilms tumors (VLRWT) as stage I favorable histology Wilms tumors weighing less than 550 g in children younger than 24 months of age. VLRWTs may be treated with nephrectomy alone. However, 10% to 15% of VLRWTs relapse without chemotherapy....

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Hlavní autoři: Perlman, Elizabeth J., Grundy, Paul E., Anderson, James R., Jennings, Lawrence J., Green, Daniel M., Dome, Jeffrey S., Shamberger, Robert C., Ruteshouser, E. Cristy, Huff, Vicki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2011
Témata:
Original Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056654/
https://ncbi.nlm.nih.gov/pubmed/21189373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.31.5192
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