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Histone deacetylase inhibitors: molecular mechanisms of action and clinical trials as anti-cancer drugs

Histone deacetylase (HDAC) inhibitors are a relatively new class of anti-cancer agents that play important roles in epigenetic or non-epigenetic regulation, inducing death, apoptosis, and cell cycle arrest in cancer cells. Recently, their use has been clinically validated in cancer patients resultin...

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Bibliografiska uppgifter
Huvudupphovsmän: Kim, Hyun-Jung, Bae, Suk-Chul
Materialtyp: Artigo
Språk:Inglês
Publicerad: e-Century Publishing Corporation 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056563/
https://ncbi.nlm.nih.gov/pubmed/21416059
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