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Tailed duplex DNA is the preferred substrate for Rad51 protein-mediated homologous pairing

The repair of potentially lethal DNA double-stranded breaks (DSBs) by homologous recombination requires processing of the broken DNA into a resected DNA duplex with a protruding 3′-single-stranded DNA (ssDNA) tail. Accordingly, the canonical models for DSB repair require invasion of an intact homolo...

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Bibliografiske detaljer
Main Authors: Mazin, Alexander V., Zaitseva, Elena, Sung, Patrick, Kowalczykowski, Stephen C.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC305653/
https://ncbi.nlm.nih.gov/pubmed/10698955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.5.1148
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