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Prophylaxis of Graft-Versus-Host Disease in Unrelated Donor Transplantation With Pentostatin, Tacrolimus, and Mini-Methotrexate: A Phase I/II Controlled, Adaptively Randomized Study

PURPOSE: Acute graft-versus-host disease (aGVHD) is a major cause of morbidity and mortality after matched unrelated, related, or mismatched related donor hematopoietic stem-cell transplantation (HSCT). Improved GVHD prevention methods are needed. Pentostatin, an adenosine deaminase inhibitor, leads...

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Main Authors: Parmar, Simrit, Andersson, Borje S., Couriel, Daniel, Munsell, Mark F., Fernandez-Vina, Marcelo, Jones, Roy B., Shpall, Elizabeth J., Popat, Uday, Anderlini, Paolo, Giralt, Sergio, Alousi, Amin, Cano, Pedro, Bosque, Doyle, Hosing, Chitra, de Padua Silva, Leandro, Westmoreland, Michael, Wathen, J. Kyle, Berry, Donald, Champlin, Richard E., de Lima, Marcos J.
格式: Artigo
語言:Inglês
出版: American Society of Clinical Oncology 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056464/
https://ncbi.nlm.nih.gov/pubmed/21149654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.30.6357
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