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Measurement of mechanical tractions exerted by cells within three-dimensional matrices

Quantitative measurements of cell-generated forces have heretofore required that cells be cultured on two-dimensional substrates. We describe a technique to quantitatively measure three-dimensional traction forces exerted by cells fully encapsulated within well-defined elastic hydrogel matrices. We...

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Detalhes bibliográficos
Main Authors: Legant, Wesley R., Miller, Jordan S., Blakely, Brandon L., Cohen, Daniel M., Genin, Guy M., Chen, Christopher S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056435/
https://ncbi.nlm.nih.gov/pubmed/21076420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1531
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