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Single-molecule analysis of a molecular disassemblase reveals the mechanism of Hsc70-driven clathrin uncoating

Heat shock cognate protein 70 (Hsc70) supports remodeling of protein complexes -- for example, disassembly of clathrin coats on endocytic coated vesicles. To understand how a simple ATP driven molecular clamp catalyzes a large-scale disassembly reaction, we have used single-particle fluorescence ima...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Böcking, Till, Aguet, François, Harrison, Stephen C., Kirchhausen, Tomas
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056279/
https://ncbi.nlm.nih.gov/pubmed/21278753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1985
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