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Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene

Many different chromosomal translocations occur in man at chromosome 11q23 in acute leukaemias. Molecular analyses revealed that the MLL gene (also called ALL–1, HRX or HTRX) is broken by the translocations, causing fusion with genes from other chromosomes. The diversity of MLL fusion partners poses...

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Detalhes bibliográficos
Main Authors: Dobson, Claire L., Warren, Alan J., Pannell, Richard, Forster, Alan, Rabbitts, Terence H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC305624/
https://ncbi.nlm.nih.gov/pubmed/10698926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.5.843
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