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Regulatory Haplotypes in ARG1 Are Associated with Altered Bronchodilator Response

Rationale: β(2)-agonists, the most common treatment for asthma, have a wide interindividual variability in response, which is partially attributed to genetic factors. We previously identified single nucleotide polymorphisms in the arginase 1 (ARG1) gene, which are associated with β(2)-agonist bronch...

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Main Authors: Duan, Qing Ling, Gaume, Brigitte R., Hawkins, Gregory A., Himes, Blanca E., Bleecker, Eugene R., Klanderman, Barbara, Irvin, Charles G., Peters, Stephen P., Meyers, Deborah A., Hanrahan, John P., Lima, John J., Litonjua, Augusto A., Tantisira, Kelan G., Liggett, Stephen B.
格式: Artigo
語言:Inglês
出版: American Thoracic Society 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056223/
https://ncbi.nlm.nih.gov/pubmed/20851928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201005-0758OC
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