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Regulatory Haplotypes in ARG1 Are Associated with Altered Bronchodilator Response

Rationale: β(2)-agonists, the most common treatment for asthma, have a wide interindividual variability in response, which is partially attributed to genetic factors. We previously identified single nucleotide polymorphisms in the arginase 1 (ARG1) gene, which are associated with β(2)-agonist bronch...

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Bibliographische Detailangaben
Hauptverfasser: Duan, Qing Ling, Gaume, Brigitte R., Hawkins, Gregory A., Himes, Blanca E., Bleecker, Eugene R., Klanderman, Barbara, Irvin, Charles G., Peters, Stephen P., Meyers, Deborah A., Hanrahan, John P., Lima, John J., Litonjua, Augusto A., Tantisira, Kelan G., Liggett, Stephen B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056223/
https://ncbi.nlm.nih.gov/pubmed/20851928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201005-0758OC
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