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Regulatory Haplotypes in ARG1 Are Associated with Altered Bronchodilator Response

Rationale: β(2)-agonists, the most common treatment for asthma, have a wide interindividual variability in response, which is partially attributed to genetic factors. We previously identified single nucleotide polymorphisms in the arginase 1 (ARG1) gene, which are associated with β(2)-agonist bronch...

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Hlavní autoři: Duan, Qing Ling, Gaume, Brigitte R., Hawkins, Gregory A., Himes, Blanca E., Bleecker, Eugene R., Klanderman, Barbara, Irvin, Charles G., Peters, Stephen P., Meyers, Deborah A., Hanrahan, John P., Lima, John J., Litonjua, Augusto A., Tantisira, Kelan G., Liggett, Stephen B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056223/
https://ncbi.nlm.nih.gov/pubmed/20851928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201005-0758OC
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