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Regulatory Haplotypes in ARG1 Are Associated with Altered Bronchodilator Response

Rationale: β(2)-agonists, the most common treatment for asthma, have a wide interindividual variability in response, which is partially attributed to genetic factors. We previously identified single nucleotide polymorphisms in the arginase 1 (ARG1) gene, which are associated with β(2)-agonist bronch...

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Autors principals: Duan, Qing Ling, Gaume, Brigitte R., Hawkins, Gregory A., Himes, Blanca E., Bleecker, Eugene R., Klanderman, Barbara, Irvin, Charles G., Peters, Stephen P., Meyers, Deborah A., Hanrahan, John P., Lima, John J., Litonjua, Augusto A., Tantisira, Kelan G., Liggett, Stephen B.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056223/
https://ncbi.nlm.nih.gov/pubmed/20851928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201005-0758OC
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