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Expanded Repertoire of AAV Vector Serotypes Mediate Unique Patterns of Transduction in Mouse Brain

A wide diversity of adeno-associated virus (AAV) structural proteins uncovered from latent genomes in primate tissue has expanded the number of AAV vector serotypes, which can potentially confer unique cell tropism to the vector. We evaluated 17 of these vectors in the mouse brain using green fluore...

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Bibliographic Details
Main Authors: Cearley, Cassia N., Vandenberghe, Luk H, Parente, Michael K, Carnish, Erin R, Wilson, James M, Wolfe, John H
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056207/
https://ncbi.nlm.nih.gov/pubmed/18714307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.166
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