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Dengue vaccine trial guidelines and role of large-scale, post proof-of-concept demonstration projects in bringing a dengue vaccine to use in dengue endemic areas

In this review, we consider the issues impacting conduct and design of dengue vaccine trials with reference to the recently published world Health Organization “Guidelines for Conduct of Clinical Trials of Dengue vaccines in endemic Areas.” We discuss logistic, scientific and ethical challenges conc...

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מידע ביבליוגרפי
Main Authors: Letson, G William, Singhasivanon, Pratap, Fernandez, Eduardo, Abeysinghe, Nihal, Amador, Juan Jose, Margolis, Harold S, Edelman, Robert
פורמט: Artigo
שפה:Inglês
יצא לאור: Landes Bioscience 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056064/
https://ncbi.nlm.nih.gov/pubmed/20935506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.6.12.13018
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