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Dengue vaccine trial guidelines and role of large-scale, post proof-of-concept demonstration projects in bringing a dengue vaccine to use in dengue endemic areas
In this review, we consider the issues impacting conduct and design of dengue vaccine trials with reference to the recently published world Health Organization “Guidelines for Conduct of Clinical Trials of Dengue vaccines in endemic Areas.” We discuss logistic, scientific and ethical challenges conc...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3056064/ https://ncbi.nlm.nih.gov/pubmed/20935506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.6.12.13018 |
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