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Exploring a glycolytic inhibitor for the treatment of an FH-deficient type-2 papillary RCC

BACKGROUND: A 24-year-old woman presented with a 45 cm complex cystic renal mass, which was resected. The tumor was a type-2 papillary renal cell carcinoma (pRCC-2), and several nodules remained. The patient was treated with mammalian target of rapamycin complex 1 (mTORC1) inhibitors, but after 5 mo...

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Detalhes bibliográficos
Main Authors: Yamasaki, Toshinari, Tran, Tram Anh T., Oz, Orhan K., Raj, Ganesh V., Schwarz, Roderich E., DeBerardinis, Ralph J., Zhang, Xuewu, Brugarolas, James
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055922/
https://ncbi.nlm.nih.gov/pubmed/21304509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrurol.2010.234
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