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Utilization of IκB–EGFP Chimeric Gene as an Indicator to Identify Microbial Metabolites with NF-κB Inhibitor Activity

NF-κB regulates several important expressions, such as cytokine release, anti-apoptosis, adhesion molecule expression, and cell cycle processing. Several NF-κB inhibitors have been discovered as an anti-tumor or anti-inflammatory drug. The activity of NF-κB transcription factor is negatively regulat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lin, Yu-Ling, Chen, Yen-Shun, Hsieh, Jui-Hung, Lin, Ching-Min, Wu, Hsin-Yi, Lin, Chen-Si, Chu, Rea-Min, Liao, Kuang-Wen, Hsu, Yuan-Hsun
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055915/
https://ncbi.nlm.nih.gov/pubmed/21406073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12575-010-9033-9
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