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BMP-12 Treatment of Adult Mesenchymal Stem Cells In Vitro Augments Tendon-Like Tissue Formation and Defect Repair In Vivo

We characterized the differentiation of rat bone marrow-derived mesenchymal stem cells (BM-MSCs) into tenocyte-like cells in response to bone morphogenetic protein-12 (BMP-12). BM-MSCs were prepared from Sprague-Dawley rats and cultured as monolayers. Recombinant BMP-12 treatment (10 ng/ml) of BM-MS...

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Bibliografski detalji
Glavni autori: Lee, Jonathan Y., Zhou, Zuping, Taub, Peter J., Ramcharan, Melissa, Li, Yonghui, Akinbiyi, Takintope, Maharam, Edward R., Leong, Daniel J., Laudier, Damien M., Ruike, Takuya, Torina, Phillip J., Zaidi, Mone, Majeska, Robert J., Schaffler, Mitchell B., Flatow, Evan L., Sun, Hui B.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055887/
https://ncbi.nlm.nih.gov/pubmed/21412429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017531
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