High-throughput 454 resequencing for allele discovery and recombination mapping in Plasmodium falciparum

BACKGROUND: Knowledge of the origins, distribution, and inheritance of variation in the malaria parasite (Plasmodium falciparum) genome is crucial for understanding its evolution; however the 81% (A+T) genome poses challenges to high-throughput sequencing technologies. We explore the viability of th...

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Autori principali: Samarakoon, Upeka, Regier, Allison, Tan, Asako, Desany, Brian A, Collins, Brendan, Tan, John C, Emrich, Scott J, Ferdig, Michael T
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Methodology Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055840/
https://ncbi.nlm.nih.gov/pubmed/21324207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-116
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