A carregar...

Intralysosomal Iron Induces Lysosomal Membrane Permeabilization and Cathepsin D–Mediated Cell Death in Trabecular Meshwork Cells Exposed to Oxidative Stress

PURPOSE. To investigate the role of intralysosomal redox-active iron in oxidative stress-induced damage in trabecular meshwork (TM) cells. METHODS. Chronic oxidative stress was applied using the hyperoxic model; acute oxidative stress was applied with H(2)O(2). Microarray analysis was performed usin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lin, Yizhi, Epstein, David L., Liton, Paloma B.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055766/
https://ncbi.nlm.nih.gov/pubmed/20574010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5410
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!