In Vivo Binding of Antipsychotics to D(3) and D(2) Receptors: A PET Study in Baboons with [(11)C]-(+)-PHNO

Measuring the in vivo occupancy of antipsychotic drugs at dopamine D(2) and D(3) receptors separately has been difficult because of the lack of selective radiotracers. The recently developed [(11)C]-(+)-PHNO is D(3)-preferring, allowing estimates of the relative D(2) and D(3) binding of antipsychoti...

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Bibliographische Detailangaben
Hauptverfasser: Girgis, Ragy R, Xu, Xiaoyan, Miyake, Nobumi, Easwaramoorthy, Balu, Gunn, Roger N, Rabiner, Eugenii A, Abi-Dargham, Anissa, Slifstein, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055723/
https://ncbi.nlm.nih.gov/pubmed/21178982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.228
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