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14-3-3 proteins block apoptosis and differentially regulate MAPK cascades

14-3-3 family members are dimeric phosphoserine-binding proteins that participate in signal transduction and checkpoint control pathways. In this work, dominant-negative mutant forms of 14-3-3 were used to disrupt 14-3-3 function in cultured cells and in transgenic animals. Transfection of cultured...

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Detalhes bibliográficos
Main Authors: Xing, Heming, Zhang, Shaosong, Weinheimer, Carla, Kovacs, Attila, Muslin, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC305572/
https://ncbi.nlm.nih.gov/pubmed/10654934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.3.349
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