Targeted expression of baculovirus p35 caspase inhibitor in oligodendrocytes protects mice against autoimmune-mediated demyelination

The mechanisms underlying oligodendrocyte (OLG) loss and the precise roles played by OLG death in human demyelinating diseases such as multiple sclerosis (MS), and in the rodent model of MS, experimental autoimmune encephalomyelitis (EAE), remain to be elucidated. To clarify the involvement of OLG d...

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Auteurs principaux: Hisahara, Shin, Araki, Takashi, Sugiyama, Fumihiro, Yagami, Ken–ichi, Suzuki, Misao, Abe, Kuniya, Yamamura, Ken–ichi, Miyazaki, Jun–ichi, Momoi, Takashi, Saruta, Takao, Bernard, Claude C.A., Okano, Hideyuki, Miura, Masayuki
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2000
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC305571/
https://ncbi.nlm.nih.gov/pubmed/10654933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.3.341
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