Targeted expression of baculovirus p35 caspase inhibitor in oligodendrocytes protects mice against autoimmune-mediated demyelination

The mechanisms underlying oligodendrocyte (OLG) loss and the precise roles played by OLG death in human demyelinating diseases such as multiple sclerosis (MS), and in the rodent model of MS, experimental autoimmune encephalomyelitis (EAE), remain to be elucidated. To clarify the involvement of OLG d...

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Publicado en:EMBO J
Main Authors: Hisahara, Shin, Araki, Takashi, Sugiyama, Fumihiro, Yagami, Ken–ichi, Suzuki, Misao, Abe, Kuniya, Yamamura, Ken–ichi, Miyazaki, Jun–ichi, Momoi, Takashi, Saruta, Takao, Bernard, Claude C.A., Okano, Hideyuki, Miura, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2000
Assuntos:
Articles
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305571/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10654933/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.3.341
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