Deconstructing Antiobesity Compound Action: Requirement of Serotonin 5-HT(2B) Receptors for Dexfenfluramine Anorectic Effects

The now-banned anorectic molecule, dexfenfluramine, promotes serotonin release through a serotonin transporter-dependent mechanism, and it has been widely prescribed for the treatment of obesity. Previous studies have identified that 5-HT(2B) receptors have important roles in dexfenfluramine side ef...

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Autori principali: Banas, Sophie M, Doly, Stéphane, Boutourlinsky, Katia, Diaz, Silvina L, Belmer, Arnauld, Callebert, Jacques, Collet, Corinne, Launay, Jean-Marie, Maroteaux, Luc
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055663/
https://ncbi.nlm.nih.gov/pubmed/20927048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.173
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