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Serotonin 5-HT(2B) Receptors Are Required for 3,4-Methylenedioxymethamphetamine-Induced Hyperlocomotion and 5-HT Release In Vivo and In Vitro

The “club drug” 3,4-methylenedioxymethamphetamine (MDMA; also known as ecstasy) binds preferentially to and reverses the activity of the serotonin transporter, causing release of serotonin [5-hydroxytryptamine (5-HT)] stores from nerve terminals. Subsequent activation of postsynaptic 5-HT receptors...

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Foilsithe in:J Neurosci
Main Authors: Doly, Stéphane, Valjent, Emmanuel, Setola, Vincent, Callebert, Jacques, Hervé, Denis, Launay, Jean-Marie, Maroteaux, Luc
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670669/
https://ncbi.nlm.nih.gov/pubmed/18337424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5723-07.2008
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