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A novel RNA binding protein, SBP2, is required for the translation of mammalian selenoprotein mRNAs
In eukaryotes, the decoding of the UGA codon as selenocysteine (Sec) requires a Sec insertion sequence (SECIS) element in the 3′ untranslated region of the mRNA. We purified a SECIS binding protein, SBP2, and obtained a cDNA clone that encodes this activity. SBP2 is a novel protein containing a puta...
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| Published in: | EMBO J |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2000
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305564/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10637234/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.2.306 |
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