A Novel Mechanism and Treatment Target for Presynaptic Abnormalities in Specific Striatal Regions in Schizophrenia

Abnormalities of amount and function of presynaptic terminals may have an important role in the mechanism of illness in schizophrenia. The SNARE proteins (SNAP-25, syntaxin, and VAMP) are enriched in presynaptic terminals, where they interact to form a functional complex to facilitate vesicle fusion...

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Autores principales: Barakauskas, Vilte E, Beasley, Clare L, Barr, Alasdair M, Ypsilanti, Athena R, Li, Hong-Ying, Thornton, Allen E, Wong, Hubert, Rosokilja, Gorazd, Mann, J John, Mancevski, Branislav, Jakovski, Zlatko, Davceva, Natasha, Ilievski, Boro, Dwork, Andrew J, Falkai, Peter, Honer, William G
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2010
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055413/
https://ncbi.nlm.nih.gov/pubmed/20072114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2009.228
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