A Novel Mechanism and Treatment Target for Presynaptic Abnormalities in Specific Striatal Regions in Schizophrenia

Abnormalities of amount and function of presynaptic terminals may have an important role in the mechanism of illness in schizophrenia. The SNARE proteins (SNAP-25, syntaxin, and VAMP) are enriched in presynaptic terminals, where they interact to form a functional complex to facilitate vesicle fusion...

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Detalhes bibliográficos
Main Authors: Barakauskas, Vilte E, Beasley, Clare L, Barr, Alasdair M, Ypsilanti, Athena R, Li, Hong-Ying, Thornton, Allen E, Wong, Hubert, Rosokilja, Gorazd, Mann, J John, Mancevski, Branislav, Jakovski, Zlatko, Davceva, Natasha, Ilievski, Boro, Dwork, Andrew J, Falkai, Peter, Honer, William G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055413/
https://ncbi.nlm.nih.gov/pubmed/20072114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2009.228
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