Dopaminergic Signaling Mediates the Motivational Response Underlying the Opponent Process to Chronic but Not Acute Nicotine

The mesolimbic dopamine (DA) system is implicated in the processing of the positive reinforcing effect of all drugs of abuse, including nicotine. It has been suggested that the dopaminergic system is also involved in the aversive motivational response to drug withdrawal, particularly for opiates, ho...

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Detalhes bibliográficos
Main Authors: Grieder, Taryn E, Sellings, Laurie H, Vargas-Perez, Hector, Ting-A-Kee, Ryan, Siu, Eric C, Tyndale, Rachel F, van der Kooy, Derek
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055371/
https://ncbi.nlm.nih.gov/pubmed/20032966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2009.198
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