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Is Glycogen Synthase Kinase-3 a Central Modulator in Mood Regulation?

Little is known regarding the mechanisms underlying the complex etiology of mood disorders, represented mainly by major depressive disorder and bipolar disorder. The 1996 discovery that lithium inhibits glycogen synthase kinase-3 (GSK3) raised the possibility that impaired inhibition of GSK3 is asso...

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Detalhes bibliográficos
Main Authors: Li, Xiaohua, Jope, Richard S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055312/
https://ncbi.nlm.nih.gov/pubmed/20668436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.105
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