Autotaxin is induced by TSA through HDAC3 and HDAC7 inhibition and antagonizes the TSA-induced cell apoptosis

BACKGROUND: Autotaxin (ATX) is a secreted glycoprotein with the lysophospholipase D (lysoPLD) activity to convert lysophosphatidylcholine (LPC) into lysophosphatidic acid (LPA), a bioactive lysophospholipid involved in diverse biological actions. ATX is highly expressed in some cancer cells and cont...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Li, Song, Wang, Baolu, Xu, Yan, Zhang, Junjie
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055229/
https://ncbi.nlm.nih.gov/pubmed/21314984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-18
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares