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Expression of osteoprotegerin and RANK ligand in breast cancer bone metastasis.

Bone destruction is primarily mediated by osteoclastic bone resorption, and cancer cells stimulate the formation and activation of osteoclasts next to metastatic foci. Accumulating evidences indicate that receptor activator of NF-kB ligand (RANKL) is the ultimate extracellular mediator that stimulat...

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Autors principals: Park, Hye-Rim, Min, Soo-Kee, Cho, Hyun-Deuk, Kim, Duck-Hwan, Shin, Hyung Sik, Park, Young Euy
Format: Artigo
Idioma:Inglês
Publicat: Korean Academy of Medical Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055084/
https://ncbi.nlm.nih.gov/pubmed/12923331
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