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Role of large thermal fluctuations and magnesium ions in t-RNA selectivity of the ribosome

The fidelity of translation selection begins with the base pairing of codon-anticodon complex between the m-RNA and tRNAs. Binding of cognate and near-cognate tRNAs induces 30S subunit of the ribosome to wrap around the ternary complex, EF-Tu(GTP)aa-tRNA. We have proposed that large thermal fluctuat...

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Autori principali: Guo, Zuojun, Gibson, Meghan, Sitha, Sanyasi, Chu, Steven, Mohanty, Udayan
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3054037/
https://ncbi.nlm.nih.gov/pubmed/21368154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100671108
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