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Molecular basis of substrate-induced permeation by an amino acid antiporter

Transporters of the amino acid, polyamine and organocation (APC) superfamily play essential roles in cell redox balance, cancer, and aminoacidurias. The bacterial L-arginine/agmatine antiporter, AdiC, is the main APC structural paradigm and shares the “5 + 5 inverted repeat” fold found in other fami...

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Detalles Bibliográficos
Main Authors: Kowalczyk, Lukasz, Ratera, Mercè, Paladino, Antonella, Bartoccioni, Paola, Errasti-Murugarren, Ekaitz, Valencia, Eva, Portella, Guillem, Bial, Susanna, Zorzano, Antonio, Fita, Ignacio, Orozco, Modesto, Carpena, Xavier, Vázquez-Ibar, José Luis, Palacín, Manuel
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3054010/
https://ncbi.nlm.nih.gov/pubmed/21368142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018081108
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