L amino acid transporter structure and molecular bases for the asymmetry of substrate interaction

L-amino acid transporters (LATs) play key roles in human physiology and are implicated in several human pathologies. LATs are asymmetric amino acid exchangers where the low apparent affinity cytoplasmic side controls the exchange of substrates with high apparent affinity on the extracellular side. H...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Errasti-Murugarren, Ekaitz, Fort, Joana, Bartoccioni, Paola, Díaz, Lucía, Pardon, Els, Carpena, Xavier, Espino-Guarch, Meritxell, Zorzano, Antonio, Ziegler, Christine, Steyaert, Jan, Fernández-Recio, Juan, Fita, Ignacio, Palacín, Manuel
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472337/
https://ncbi.nlm.nih.gov/pubmed/31000719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09837-z
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