Sustained TL1A expression modulates effector and regulatory T-cell responses and drives intestinal goblet cell hyperplasia

The tumor necrosis factor (TNF) superfamily protein TNF-like 1A (TL1A) is the ligand for death receptor 3 (DR3). TL1A is induced on activated dendritic cells (DCs) and its expression has been linked to human inflammatory bowel disease. To address how TL1A might influence intestinal inflammation, we...

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Main Authors: Taraban, VY, Slebioda, TJ, Willoughby, JE, Buchan, SL, James, S, Sheth, B, Smyth, NR, Thomas, GJ, Wang, ECY, Al-Shamkhani, A
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053556/
https://ncbi.nlm.nih.gov/pubmed/20962771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2010.70
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