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Nanoengineered Surfaces Enhance Drug Loading and Adhesion

To circumvent the barriers encountered by macromolecules at the gastrointestinal mucosa, sufficient therapeutic must be delivered in close proximity to cells1. Previously, we have shown that silicon nanowires penetrate the mucous layer and adhere directly to cells under high shear2. In this work, we...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fischer, Kathleen E., Jayagopal, Aishwarya, Nagaraj, Ganesh, Daniels, R. Hugh, Li, Esther M., Silvestrini, Matthew T., Desai, Tejal A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053427/
https://ncbi.nlm.nih.gov/pubmed/21280638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl103951e
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