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Nanoengineered Surfaces Enhance Drug Loading and Adhesion

To circumvent the barriers encountered by macromolecules at the gastrointestinal mucosa, sufficient therapeutic must be delivered in close proximity to cells1. Previously, we have shown that silicon nanowires penetrate the mucous layer and adhere directly to cells under high shear2. In this work, we...

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Bibliografiske detaljer
Main Authors: Fischer, Kathleen E., Jayagopal, Aishwarya, Nagaraj, Ganesh, Daniels, R. Hugh, Li, Esther M., Silvestrini, Matthew T., Desai, Tejal A.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053427/
https://ncbi.nlm.nih.gov/pubmed/21280638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl103951e
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