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Nanoengineered Surfaces Enhance Drug Loading and Adhesion

To circumvent the barriers encountered by macromolecules at the gastrointestinal mucosa, sufficient therapeutic must be delivered in close proximity to cells1. Previously, we have shown that silicon nanowires penetrate the mucous layer and adhere directly to cells under high shear2. In this work, we...

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Detalhes bibliográficos
Main Authors: Fischer, Kathleen E., Jayagopal, Aishwarya, Nagaraj, Ganesh, Daniels, R. Hugh, Li, Esther M., Silvestrini, Matthew T., Desai, Tejal A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053427/
https://ncbi.nlm.nih.gov/pubmed/21280638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl103951e
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