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Cell Proliferation and Interleukin-6–Type Cytokine Signaling Are Implicated by Gene Expression Responses in Early Optic Nerve Head Injury in Rat Glaucoma

PURPOSE. In glaucoma, the optic nerve head (ONH) is the principal site of initial axonal injury, and elevated intraocular pressure (IOP) is the predominant risk factor. However, the initial responses of the ONH to elevated IOP are unknown. Here the authors use a rat glaucoma model to characterize ON...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Johnson, Elaine C., Doser, Thomas A., Cepurna, William O., Dyck, Jennifer A., Jia, Lijun, Guo, Ying, Lambert, Wendi S., Morrison, John C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Association for Research in Vision and Ophthalmology, Inc. 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053294/
https://ncbi.nlm.nih.gov/pubmed/20847120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5317
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